N closest Genes to a given location

Hi,

This is basically an extension of the following question already asked in biostar (http://biostars.org/post/show/53561/python-finding-gene-closest-to-a-given-location/).

Let us say I have a list of genomic regions (as a bed file), and also a list of genes (as a bed file). For each genomic region I want to find the 5 (or N to be general) closest genes. How would I try to do that? Any suggestions?

Thanks!